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1

Control of the ToxR virulence regulon in Vibrio cholerae by environmental stimuli

Karen Skorupski, Ronald K. Taylor

Journal:

Molecular Microbiology

Year:

1997

Language:

english

File:

PDF, 422 KB

english, 1997

2

A new level in the Vibrio cholerae ToxR virulence cascade: AphA is required for transcriptional activation of the tcpPH operon

Karen Skorupski, Ronald K. Taylor

Journal:

Molecular Microbiology

Year:

1999

Language:

english

File:

PDF, 761 KB

english, 1999

3

Overlapping binding sites for the virulence gene regulators AphA, AphB and cAMP-CRP at the Vibrio cholerae tcpPH promoter

Gabriela Kovacikova, Karen Skorupski

Journal:

Molecular Microbiology

Year:

2001

Language:

english

File:

PDF, 2.19 MB

english, 2001

4

Binding site requirements of the virulence gene regulator AphB: differential affinities for the Vibrio cholerae classical and El Tor tcpPH promoters

Gabriela Kovacikova, Karen Skorupski

Journal:

Molecular Microbiology

Year:

2002

Language:

english

File:

PDF, 680 KB

english, 2002

5

Regulation of virulence gene expression in Vibrio cholerae by quorum sensing: HapR functions at the aphA promoter

Gabriela Kovacikova, Karen Skorupski

Journal:

Molecular Microbiology

Year:

2002

Language:

english

File:

PDF, 309 KB

english, 2002

6

Vibrio cholerae AphA uses a novel mechanism for virulence gene activation that involves interaction with the LysR-type regulator AphB at the tcpPH promoter

Gabriela Kovacikova, Wei Lin, Karen Skorupski

Journal:

Molecular Microbiology

Year:

2004

Language:

english

File:

PDF, 216 KB

english, 2004

7

Dual regulation of genes involved in acetoin biosynthesis and motility/biofilm formation by the virulence activator AphA and the acetate-responsive LysR-type regulator AlsR in Vibrio cholerae

Gabriela Kovacikova, Wei Lin, Karen Skorupski

Journal:

Molecular Microbiology

Year:

2005

Language:

english

File:

PDF, 395 KB

english, 2005

8

The quorum sensing regulator HapR downregulates the expression of the virulence gene transcription factor AphA in Vibrio cholerae by antagonizing Lrp- and VpsR-mediated activation

Wei Lin, Gabriela Kovacikova, Karen Skorupski

Journal:

Molecular Microbiology

Year:

2007

Language:

english

File:

PDF, 727 KB

english, 2007

9

The crystal structure of AphB, a virulence gene activator from Vibrio cholerae, reveals residues that influence its response to oxygen and pH

Jennifer L. Taylor, Rukman S. De Silva, Gabriela Kovacikova, Wei Lin, Ronald K. Taylor, Karen Skorupski, F. Jon Kull

Journal:

Molecular Microbiology

Year:

2012

Language:

english

File:

PDF, 1.49 MB

english, 2012

10

Efficacy and Toxicity of Intracavitary Administration of Pegylated Liposomal Encapsulated Doxorubicin (DOXIL) in Dogs with Hemangiosarcoma

Karin Sorenmo, Marissa Samluk, Craig Clifford, Jennifer Baez, Beth Overley, Katherine Skorupski, Karen Oberthaler, Jeffrey Barrett, Tom Van Winkle, Gabriela Seiler, Robert Poppenga, Frances Shofer

Journal:

Veterinary and Comparative Oncology

Year:

2005

Language:

english

File:

PDF, 196 KB

english, 2005

11

Purification and DNA-Binding Activity of the PacA Subunit of the Bacteriophage P1 Pacase Enzyme

Karen Skorupski, Nat Sternberg, Brian Sauer

Journal:

Journal of Molecular Biology

Year:

1994

File:

PDF, 780 KB

1994

12

Faithful Cleavage of the P1 Packaging Site (pac) Requires Two Phage Proteins, PacA and PacB, and Two Escherichia coli Proteins, IHF and HU

Karen Skorupski, Brian Sauer, Nat Sternberg

Journal:

Journal of Molecular Biology

Year:

1994

File:

PDF, 1.15 MB

1994

13

Bacteriophage P1 genes involved in the recognition and cleavage of the phage packaging site (pac)

Karen Skorupski, James C. Pierce, Brian Sauer, Nat Sternberg

Journal:

Journal of Molecular Biology

Year:

1992

Language:

english

File:

PDF, 2.31 MB

english, 1992

14

Positive selection vectors for allelic exchange

Karen Skorupski, Ronald K. Taylor

Journal:

Year:

1996

Language:

english

File:

PDF, 523 KB

english, 1996

15

Parallel Quorum Sensing Systems Converge to Regulate Virulence in Vibrio cholerae

Melissa B. Miller, Karen Skorupski, Derrick H. Lenz, Ronald K. Taylor, Bonnie L. Bassler

Journal:

Year:

2002

Language:

english

File:

PDF, 312 KB

english, 2002

16

Sequence and functional analysis of the gene encoding Vibrio cholerae cAMP receptor protein

Karen Skorupski, Ronald K Taylor

Journal:

Year:

1997

Language:

english

File:

PDF, 412 KB

english, 1997

17

Clinical and Pharmacokinetic Characteristics of Intracavitary Administration of Pegylated Liposomal Encapsulated Doxorubicin in Dogs with Splenic Hemangiosarcoma

Karin Sorenmo, Marissa Samluk, Craig Clifford, Jennifer Baez, Jeffrey S. Barrett, Robert Poppenga, Beth Overley, Katherine Skorupski, Karen Oberthaler, Tom Van Winkle, Gabriela Seller, Frances Shofer

Journal:

Journal of Veterinary Internal Medicine

Year:

2007

Language:

english

File:

PDF, 391 KB

english, 2007

18

The Crystal Structure of AphB, a Virulence Gene Activator from Vibrio Cholerae, Reveals Residues that Influence its Response to Oxygen and pH

Taylor, Jennifer L., De Silva, Rukman S., Kovacikova, Gabriela, Lin, Wei, Taylor, Ronald K., Skorupski, Karen, Kull, F. Jon

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 36 KB

english, 2012

19

Cyclic AMP and its Receptor Protein Negatively Regulate the Coordinate Expression of Cholera Toxin and Toxin-Coregulated Pilus in Vibrio cholerae

Karen Skorupski and Ronald K. Taylor

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.27 MB

english, 1997

20

The 40-residue insertion in Vibrio cholerae FadR facilitates binding of an additional fatty acyl-CoA ligand

Shi, Wei, Kovacikova, Gabriela, Lin, Wei, Taylor, Ronald K., Skorupski, Karen, Kull, F. Jon

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 2.51 MB

english, 2015

21

Proteolysis of Virulence Regulator ToxR Is Associated with Entry of Vibrio cholerae into a Dormant State

Almagro-Moreno, Salvador, Kim, Tae K., Skorupski, Karen, Taylor, Ronald K., Casadesús, Josep

Journal:

Year:

2015

Language:

english

File:

PDF, 7.75 MB

english, 2015

22

Structure of Vibrio cholerae ToxT Reveals a Mechanism for Fatty Acid Regulation of Virulence Genes

Michael J. Lowden, Karen Skorupski, Maria Pellegrini, Michael G. Chiorazzo, Ronald K. Taylor, F. Jon Kull and John J. Mekalanos

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.50 MB

english, 2010

23

The Fatty Acid Regulator FadR Influences the Expression of the Virulence Cascade in the El Tor Biotype of Vibrio cholerae by Modulating the Levels of ToxT via Two Different Mechanisms

Kovacikova, Gabriela, Lin, Wei, Taylor, Ronald K., Skorupski, Karen, DiRita, Victor J.

Journal:

Journal of Bacteriology

Year:

2017

Language:

english

File:

PDF, 2.49 MB

english, 2017

24

Bile salts and alkaline pH reciprocally modulate the interaction between the periplasmic domains of Vibrio cholerae ToxR and ToxS

Midgett, Charles R, Almagro-Moreno, Salvador, Pellegrini, Maria, Taylor, Ronald K, Skorupski, Karen, Kull, F. Jon

Journal:

Molecular Microbiology

Year:

2017

Language:

english

File:

PDF, 12.36 MB

english, 2017

25

Identification of a Small Molecule Activator for AphB, a LysR-Type Virulence Transcriptional Regulator in Vibrio cholerae

Privett, Britney, Pellegrini, Maria, Kovacikova, Gabriela, Taylor, Ronald, Skorupski, Karen, Mierke, Dale F., Kull, F. Jon

Journal:

Year:

2017

Language:

english

File:

PDF, 1.60 MB

english, 2017

26

Structural basis for virulence regulation in Vibrio cholerae by unsaturated fatty acid components of bile

Cruite, Justin T., Kovacikova, Gabriela, Clark, Kenzie A., Woodbrey, Anne K., Skorupski, Karen, Kull, F. Jon

Journal:

Communications Biology

Year:

2019

File:

PDF, 2.08 MB

2019